Description:
Submarine Gel Electrophoresis System is a widely used technique in laboratories to analyze DNA based on their size and charge. In this method, the agarose gel is formed on a supporting plate, and then the plate is submerged into a tank containing a suitable electrophoresis buffer. The buffer and gel form a current bridge between the two electrode chambers. The process involves placing the molecules of interest in a gel with small pores and creating an electric field across the gel. The molecules will move faster or slower based on their size and electric charge.
Advantages:
- Wide Range of Separation: An agarose electrophoresis gel can be used to separate a much wider range of DNA and RNA sizes than a polyacrylamide gel.
- Multiple Rows of Wells: Horizontal submarine gels allow the formation of multiple rows of wells, enabling the screening of large numbers of samples on a single gel.
- Color-coded and Height Adjustable Combs: The combs used in the system are color-coded and height adjustable, making it easy to identify comb thickness at a glance and control well depth.
- Compact Tank: The system features a compact tank that reduces the buffer volume required.
- Detachable Electrodes: The electrodes in the system can be detached and replaced if needed.